Southampton continued their good start to the season with a win over Norwich on Saturday and will be keen to keep the momentum going against Southend.
Manager Harry Redknapp is keen to give some fringe players such as Theo Walcott, Nathan Dyer and Martin Crainie a chance, but the squad will still include senior players such as David Prutton, Dennis Wise, Rory Delap and Brett Ormerod.
Southend will be without star striker Freddy Eastwood, who is banned, while injured defender Duncan Jupp may be replaced by veteran Spencer Prior.
The tip is based on the personal opinion of the author. No success is guaranteed. Please gamble responsibly. 18+
Back Southampton @ 2.00
Southampton's kids had too much class for Southend and the even money odds made this bet an absolute steal.